That may help more, but this changeset seems to be hacky for now (requires in-process-gpu as it doesn’t do a proper implementation atop shared FDs) so can’t be seen as reliable.
Either way, anticheat components probably won’t run until ‘user syscall dispatch’ changes are merged in both the Linux kernel and Wine (or forks-of) and these have been validated for accuracy (which may be very inaccurate right now, even?). I believe Linux 5.11 has user syscall dispatch, optionally, but Wine never ended up using this functionality.
See my longer post, by the way: